Just found this wonderful article on cleaning up family computers (raise your hand if you haven't been tapped as the family computer geek at least once). The article, Geek to Live: How to fix Mom and Dad's computer, by Gina Tapani contains a pretty complete list of system clean up items complete with links and almost step-by-step directions.
I'm contemplating emailing the link to family members who've already said, "Maybe you could just take a look." Most likely I'll burn the CD and print out the article so I have it all in hand.
Via Coudal Partners